Case study 1: mouse kidney peptide dataset

Author

Yinyue Zhu

In this case study, we analyze a MALDI-TIMS-TOF tryptic peptide dataset of mouse kidney tissue. First we processed the data in TIMSImaging, then performed segmentation in Cardinal, in addition we compared processing workflow with/without ion mobility. The dataset is from Melanie Föll Lab and available at MassIVE (MSV000096373).
Li, M., Meyer, L., Meier, N., Witte, J., Maldacker, M., Seredynska, A., Schueler, J., Schilling, O. and Föll, M. (2025), Spatial Proteomics by Parallel Accumulation-Serial Fragmentation Supported MALDI MS/MS Imaging: A First Glance Into Multiplexed and Spatial Peptide Identification. Rapid Commun Mass Spectrom, 39: e10006. https://doi.org/10.1002/rcm.10006